Health

Diabetes After 40: 3 Ways Aging Affects Your Blood Sugar Control

Health
10 min
Jenna Ehteshami, MS, MPH, RD, LD

Why Blood Sugar Management Can Change After 40

Whether you’ve been managing diabetes for years or are newly diagnosed, it can be surprising when your blood sugar patterns shift as you age. Even with the same eating habits, activity level, and medication routine, you might notice readings creeping higher or becoming less predictable.


The truth is, aging changes how your body processes glucose. After 40, those shifts often become more noticeable. Understanding why it happens can help you adapt your approach and stay in control.

1. Reduced Muscle Mass Lowers Insulin Sensitivity

As we age, we naturally lose muscle mass (also known as “sarcopenia”) unless we actively work to maintain it. Because muscle is a major site for glucose uptake, less muscle means your body becomes less efficient at clearing sugar from the bloodstream.

  • Impact: Higher fasting blood sugar and more post-meal spikes

  • What to do: Incorporate resistance training 2–3 times per week, and include protein-rich foods to help preserve and build muscle.

2. Hormonal Changes Affect Metabolism

Even outside of menopause (what we commonly think of when someone says “hormonal shifts with age”), hormones like estrogen, testosterone, growth hormone, and cortisol shift with age as well. Some of these changes can make your body more insulin resistant.

  • Impact: Food choices or medication doses that once worked perfectly may not be as effective.

  • What to do: Monitor blood sugar more frequently, and work with your doctor and dietitian to fine-tune medication, nutrition, and activity as your needs evolve.

3. Slower Metabolism Changes How Your Body Handles Food

Digestive processes tend to slow down with age, especially after the age of 60, and your metabolism becomes less flexible. Your body may take longer to process carbohydrates, or it may store more energy as fat rather than using it for fuel.

  • Impact: Blood sugar may remain elevated for longer after meals.

  • What to do: Choose high-fiber carbs and always pair them with protein and healthy fats.

Taking Control As You Age

Getting older is inevitable, but blood sugar instability doesn’t have to be. By focusing on muscle health, staying active, eating strategically, and adjusting your plan as your body changes, you can maintain strong glucose control for decades to come.


Your 40s, 50s, and beyond can be vibrant, healthy years…especially when you understand and adapt to the ways your body evolves!